Observational Study on Treatment of Metastatic Colorectal Cancer and the Role of K-Ras

Multicentered Observational Prospective Cohort Study on the Treatment of Metastatic Colorectal Cancer and the Role of Evaluating K-Ras

The purpose of this study is to describe the treatments received and outcomes of patients with metastatic colorectal cancer, what percentage of these patients have K-Ras mutation of the tumor, and to describe the costs of treatments. Information will also be collected regarding risk factors, variables among treatment centers and patients, and explorative analyses will be done to try to identify factors that impact prognosis and factors that predict tolerability and response to treatment.

Inclusion Criteria:

• Histologic diagnosis colorectal carcinoma
• Metastatic disease
• Signed informed consent

Exclusion Criteria:

• Prior treatment of metastatic colorectal cancer
• Refusal or incapability of providing informed consent