The study investigates the effect of supra- and subgingival rinsing of 10% PVP prior to ultrasonic debridement in patients with periodontitis (as compared to rinsing with water) in terms of post treatment bacteraemia.

Study design: Randomized split-mouth (cross-over) study on 20 generally healthy subjects.

Process:

Test treatment:

• 1 min mouthwash with 10% PVP-iodine
• 1 min subgingival rinsing with 10% PVP-iodine
• 1 min ultrasonic debridement with 10% PVP-iodine as cooling liquid
• blood sampling from the V.mediana cupidi

Control:

• 1 min mouthwash with water
• 1 min subgingival rinsing with water
• 1 min ultrasonic debridement with water as cooling liquid
• blood sampling from the V.mediana cupidi

lysis, culturing and analysis of bacteria in the samples

Inclusion Criteria:

• generally healthy, adult (≥ 18 years) patients with at least two periodontal pockets of ≥ 5 mm

Exclusion Criteria:

• Pregnancy
• Lactation
• Allergy on PVP-iodine
• anticoagulation (exception 100mg/d acetylsalicylic acid)
• high risc for endocarditis
• therapeutical radiation
• participation in other clinical studies
• cognitive impairment (patient unable to understand aim and conduction of the study