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Most of colorectal polyps founded during colonoscopy are diminutive polyps less than 6 mm. However, complete removal of diminutive polyps is required to prevent tumor recurrence and development of potential interval cancers. Currently, a variety of polypectomy techniques such as hot snare, cold snare, and cold forceps polypectomy are frequently used for the removal of diminutive colorectal polyps. In regard to the completeness of polypectomy, there are few data comparing cold snare polypectomy with cold forceps biopsy technique for removal of diminutive (1-5 mm) colorectal polyps. The aim of this study is to compare cold snare polypectomy with cold forceps polypectomy using double biopsy technique for removal of diminutive colorectal polyps.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cold snare polypectomy | Experimental |
| |
| Double biopsy polypectomy | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| removal of eligible polyps using cold snare polypectomy technique | Procedure | Snare polypectomy using a mini (10 mm open diameter) size electrosurgical snare without application of electrocautery |
| Measure | Description | Time Frame |
|---|---|---|
| Complete histologic polyp eradication rate | 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Time taken for polypectomy (complete visual eradication of each polyp) | time from polyp resection to tissue retrieval | 2 weeks |
| Successful tissue retrieval rate of removed tissues | 2 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Chang Kyun Lee, MD, PhD | Kyung Hee University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kyunghee University Medical Center | Seoul | 130-702 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 14994108 | Background | Church JM. Clinical significance of small colorectal polyps. Dis Colon Rectum. 2004 Apr;47(4):481-5. doi: 10.1007/s10350-003-0078-6. Epub 2004 Mar 4. | |
| 22196811 | Background | Draganov PV, Chang MN, Alkhasawneh A, Dixon LR, Lieb J, Moshiree B, Polyak S, Sultan S, Collins D, Suman A, Valentine JF, Wagh MS, Habashi SL, Forsmark CE. Randomized, controlled trial of standard, large-capacity versus jumbo biopsy forceps for polypectomy of small, sessile, colorectal polyps. Gastrointest Endosc. 2012 Jan;75(1):118-26. doi: 10.1016/j.gie.2011.08.019. |
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| removal of eligible polyps using double biopsy technique | Procedure | Cold forceps polypectomy using a standard- capacity forceps with double biopsy technique (two bites per one forceps pass) |
|
| Rates of adverse events | Adverse events include postpolypectomy bleeding and others (polypectomy syndrome or perforation). | 4 weeks |
| Complete visual polyp eradication rate | 2 weeks |
| 21412704 | Background | Efthymiou M, Taylor AC, Desmond PV, Allen PB, Chen RY. Biopsy forceps is inadequate for the resection of diminutive polyps. Endoscopy. 2011 Apr;43(4):312-6. doi: 10.1055/s-0030-1256086. Epub 2011 Mar 16. |
| 24042189 | Derived | Lee CK, Shim JJ, Jang JY. Cold snare polypectomy vs. Cold forceps polypectomy using double-biopsy technique for removal of diminutive colorectal polyps: a prospective randomized study. Am J Gastroenterol. 2013 Oct;108(10):1593-600. doi: 10.1038/ajg.2013.302. Epub 2013 Sep 17. |