Cold Snare Versus Double Biopsy Polypectomy Technique for Removal of Diminutive Colorectal Polyps

Cold Snare Versus Double Biopsy Polypectomy Technique for Removal of Diminutive Colorectal Polyps: a Prospective Randomized Trial

Most of colorectal polyps founded during colonoscopy are diminutive polyps less than 6 mm. However, complete removal of diminutive polyps is required to prevent tumor recurrence and development of potential interval cancers. Currently, a variety of polypectomy techniques such as hot snare, cold snare, and cold forceps polypectomy are frequently used for the removal of diminutive colorectal polyps. In regard to the completeness of polypectomy, there are few data comparing cold snare polypectomy with cold forceps biopsy technique for removal of diminutive (1-5 mm) colorectal polyps. The aim of this study is to compare cold snare polypectomy with cold forceps polypectomy using double biopsy technique for removal of diminutive colorectal polyps.

Inclusion Criteria:

• Patients over the age of 20
• Informed consent

Exclusion Criteria:

• Patient undergoing antiplatelets (aspirin, clopidogrel and others) or anticoagulant therapy
• Known existing bleeding tendency (thrombocytopenia or prolonged INR)
• Inflammatory bowel diseases (Crohn's disease, or ulcerative colitis)
• ASA class III or more
• Pregnancy
• Any condition which, in the opinion of the Investigator, places the patient at unacceptable risk if he/she were to participate in the study