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The purpose of this study is to determine the effects of a deep inspiration combined to expiratory positive airway pressure protocol on respiratory function, quality of life, exercise tolerance and heart rate variability in adults with severe asthma.
Asthma is associated with high morbidity and significant mortality. This disease has functional impact on activities of daily living (ADLs) and according to some studies in the United States and Europe, the percentage of asthmatics who have significant restrictions in their ADLs is quite significant. Asthma is characterized as a major public health problem, not only in Brazil but worldwide. Currently there are few studies reporting the effects of a domiciliary program of deep inspiration associated with positive expiratory pressure in the airways of asthmatics. This study aims to analyze the benefits of this program on lung function, quality of life and response to exercise.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Deep inspiration and expiratory positive airway pressure | Experimental | The protocol of deep inspiration combined to expiratory positive airway pressure will be applied in asthmatic subjects. |
|
| Control | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Deep inspiration and positive expiratory airway pressure | Other | It was used a device the combines deep inspiration and positive expiratory airway pressure in asthmatic subjects, for 5 weeks, twice a day. |
| Measure | Description | Time Frame |
|---|---|---|
| The effect of deep inspiration and positive expiratory airway pressure in quality of life in adults with severe asthma | The quality of life will be measure by a specific questionnaire for this population 5 weeks apart. | Change in quality of life at 5 week |
| Measure | Description | Time Frame |
|---|---|---|
| The effect of deep inspiration and positive expiratory airway pressure in respiratory function in adults with severe asthma. | The respiratory function will be measure by spirometry 5 weeks apart. | Change in respiratory function at 5 week |
| The effect of deep inspiration and positive expiratory airway pressure in heart rate variability in adults with severe asthma. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pedro Dal Lago | Porto Alegre | Rio Grande do Sul | Brazil |
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The heart rate variability will be measure by the acquisition of electrocardiogram signal 5 weeks apart. |
| Change in heart rate variability at 5 week |
| The effect of deep inspiration and positive expiratory airway pressure in exercise tolerance in adults with severe asthma. | The exercise tolerance will be measure by 6 minute walk test 5 weeks apart. | Change in exercise tolerance at 5 week |