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The primary aim of the study is to assess the elasticity (Young's modulus) of cancerous tumor foci, of normal peripheral zone, and of normal transition zone in the prostate. Images obtained with the Supersonic Imagine Aixplorer scanner prior to radical prostatectomy are compared to whole-mount histology.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Elastography | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Elastography | Other | The elastography in vivo will be performed before the prostatectomy. The elastography ex vivo will be performed after radical prostatectomy. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Young's modulus(kPa) of cancerous tumor foci | 2 years | |
| Young's modulus(kPa) of normal peripheral zone | 2 years | |
| Young's modulus(kPa) of normal transition zone | 2 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| ROUVIERE Olivier, Pr | Hospices Civils de Lyon | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de Radiologie, Pavillon P Radio, Hôpital Edouard Herriot | Lyon | LYON | 69 437 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27553936 | Result | Rouviere O, Melodelima C, Hoang Dinh A, Bratan F, Pagnoux G, Sanzalone T, Crouzet S, Colombel M, Mege-Lechevallier F, Souchon R. Stiffness of benign and malignant prostate tissue measured by shear-wave elastography: a preliminary study. Eur Radiol. 2017 May;27(5):1858-1866. doi: 10.1007/s00330-016-4534-9. Epub 2016 Aug 23. |
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| ID | Term |
|---|---|
| D011471 | Prostatic Neoplasms |
| ID | Term |
|---|---|
| D005834 | Genital Neoplasms, Male |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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|
| D005832 |
| Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D011469 | Prostatic Diseases |
| D052801 | Male Urogenital Diseases |