The cystocele is the most frequent clinical shape of the genital prolapse. It is a frequent pathology in woman which can impair quality of life and generates pelvic, urinary or sexual functional disorders.

It's considered that 8 % of women will be undergo surgery in this indication before the age of 80 years. Numerous surgical techniques have been described and we distinguish the interventions according to the route (vaginal or abdominal), and according to the use or not of synthetic mesh (non-absorbable) to increase the anatomical results.

This is a multicenter, randomized, comparative, 2-parallel-arm study in patients with pelvic organ prolapse (cystocele) Approximately 260 patients aged from 45 to 75 years will be allocated to have laparoscopic sacropexy or vaginal mesh surgery.

Inclusion Criteria:

• Cystocele superior or equal to stage II of the international classification POP-Q, isolated or associated with other elements of prolapse.
• Patient must have provided written informed consent form prior to enrolment
• Patient must be insured

Exclusion Criteria:

• Previous of surgery for prolapse
• Unfavourable conditions to one or other of the 2 evaluated procedure
• Pelvic malignancy in the course of evolution
• Contraindication to the use of mesh
• Women not reading French
• Patients haven't have a social insurance
• Pregnancy or desire for future pregnancy
• To be under guardianship or deprived of liberty
• Simultaneous participation in another biomedical research