The purpose of this study was to evaluate the performance of a novel silicone hydrogel contact lens, DAILIES TOTAL1® (DT1) compared to the standard hydrogel material in 1-DAY ACUVUE® MOIST® (1DAVM) contact lens in contact lens wearers identified as having contact lens-related dryness symptoms.

Three study visits occurred over the course of 28 ± 3 days.

Inclusion Criteria:

• Be of legal age of consent and sign written Informed Consent Document and HIPAA form.
• Currently wearing soft contact lenses and identified as having contact lens-related dryness symptoms based upon responses to the Contact Lens Dry Eye Questionnaire.
• Wearing either daily disposable contact lenses or bi-weekly/monthly replacement contact lenses, daily wear use only (no extended wear use).
• Able to achieve distance visual acuity of at least 20/25 in each eye with study lenses in the available parameters, -0.50D to -6.00D.
• Willing to wear study lenses for at least 8 hours/day and at least 5 days/week.
• Willing and able to follow instructions and maintain the appointment schedule.
• Other protocol-defined inclusion criteria may apply.

Exclusion Criteria:

• Neophyte or current wearer of DAILIES TOTAL1® or 1-DAY ACUVUE® MOIST™ contact lenses.
• Requires monovision or presbyopic correction.
• Any systemic or ocular disease or disorder complicating factors or structural abnormality that would negatively affect the conduct or outcome of the study.
• Recent (within 7 days of enrollment) or current ocular infection, active ocular inflammation, glaucoma or preauricular lymphadenopathy.
• Clinically significant lash or lid abnormality.
• Systemic disease that, in the investigator's best judgment, would prohibit or confound safe contact lens wear.
• History of ocular surgery/trauma within the last 6 months.
• Topical or systemic antibiotics use within 7 days of enrollment.
• Other protocol-defined exclusion criteria may apply.

This reporting group includes all enrolled and randomized participants who completed the study.

Adverse events were collected for the duration of the study (4 months).

This reporting group includes all enrolled participants who were exposed to the test product.

The study was not powered to detect differences in individual items.