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This multicenter, prospective, non-interventional study will evaluate the prevalence and characteristics of patients with persistent symptoms of schizophrenia and the course of their illness over 24 months.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cohort |
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| Measure | Description | Time Frame |
|---|---|---|
| Course of illness: Change in Positive and Negative Syndrome Scale for Schizophrenia (PANSS) scores | from baseline to Month 24 |
| Measure | Description | Time Frame |
|---|---|---|
| Frequency/characteristics (PANSS) of patients with diagnosis of schizophrenia of >/= 12 months duration before baseline | at screening (approximately 18 months) | |
| Duration/severity of symptoms of schizophrenia according to Personal Social Performance Scale (PSP) / Health Related Quality of Life (HRQoL) questionnaire |
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Inclusion Criteria:
Patients:
Caregivers:
Exclusion Criteria:
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Patients with persistent symptoms of schizophrenia
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| Name | Affiliation | Role |
|---|---|---|
| Clinical Trials | Hoffmann-La Roche | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Buenos Aires | C1275AHG | Argentina | ||||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31908462 | Derived | Domenech C, Pastore A, Altamura AC, Bernasconi C, Corral R, Elkis H, Evans J, Malla A, Margari F, Krebs MO, Nordstroem AL, Zink M, Haro JM. Correlation of Health-Related Quality of Life in Clinically Stable Outpatients with Schizophrenia. Neuropsychiatr Dis Treat. 2019 Dec 20;15:3475-3486. doi: 10.2147/NDT.S218578. eCollection 2019. | |
| 30820841 |
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| 24 months |
| Medical resource utilization/costs | 24 months |
| Caba |
| Argentina |
| La Plata | 1900 | Argentina |
| Goiânia | Goiás | 74093-040 | Brazil |
| Curitiba | Paraná | 80240-280 | Brazil |
| São Paulo | São Paulo | 04044-000 | Brazil |
| São Paulo | São Paulo | 05403-000 | Brazil |
| Medicine Hat | Alberta | T1B 4E7 | Canada |
| Vancouver | British Columbia | V5Z 1N1 | Canada |
| Chatam | Ontario | N7L 1C1 | Canada |
| Mississauga | Ontario | L5M 4N4 | Canada |
| Windsor | Ontario | N9C 3Z4 | Canada |
| Montreal | Quebec | H2L 4M1 | Canada |
| Montreal | Quebec | H3A 1A1 | Canada |
| Québec | Quebec | G1R 2W8 | Canada |
| Verdun | Quebec | H4H 1R3 | Canada |
| Aix-en-Provence | 13100 | France |
| Chaumont | 52904 | France |
| Colmar | 68024 | France |
| Corbeil-Essonnes | 91106 | France |
| Issy-les-Moulineaux | 92133 | France |
| Lille | 59000 | France |
| Lyon | 69006 | France |
| Marseille | 13005 | France |
| Marseille | 13008 | France |
| Marseille | 13274 | France |
| Marseille | 13391 | France |
| Montberon | 31140 | France |
| Montebeliard | 25200 | France |
| Montpellier | 34295 | France |
| Nantes | 44093 | France |
| Nice | 06000 | France |
| Nice | 06100 | France |
| Paris | 75014 | France |
| Paris | 75015 | France |
| Paris | 75571 | France |
| Poitiers | 86021 | France |
| Rennes | 35703 | France |
| Rouffach | 68250 | France |
| Saint-Cyr-au-Mont-d'Or | 69450 | France |
| Tassin-la-Demi-Lune | 69160 | France |
| Toulouse | 31200 | France |
| Verdun | 55107 | France |
| Aachen | 52062 | Germany |
| Aachen | 52074 | Germany |
| Alzey | 55232 | Germany |
| Augsburg | 86156 | Germany |
| Bad Zwischenahn | 26160 | Germany |
| Berlin | 10117 | Germany |
| Berlin | 12526 | Germany |
| Berlin | 13088 | Germany |
| Berlin | 13187 | Germany |
| Bochum | 44792 | Germany |
| Cologne | 50996 | Germany |
| Dortmund | 44287 | Germany |
| Dresden | 01307 | Germany |
| Düsseldorf | 40629 | Germany |
| Ellwangen | 73479 | Germany |
| Essen | 45136 | Germany |
| Essen | 45276 | Germany |
| Grünstadt | 67269 | Germany |
| Halle | 06112 | Germany |
| Hamburg | 20246 | Germany |
| Hamburg | 22179 | Germany |
| Hamburg | 22419 | Germany |
| Hamburg | 22769 | Germany |
| Homburg/Saar | 66421 | Germany |
| Jena | 07743 | Germany |
| Koeln-Pulheim | 50259 | Germany |
| Leipzig | 04275 | Germany |
| Leipzig | 04357 | Germany |
| Magdeburg | 39120 | Germany |
| Mainz | 55131 | Germany |
| Mannheim | 68159 | Germany |
| Marburg | 35033 | Germany |
| Mittweida | 09648 | Germany |
| Oranienburg | 16515 | Germany |
| Regensburg | 93053 | Germany |
| Rostock | 18147 | Germany |
| Siegen | 57072 | Germany |
| Weinsberg | 74189 | Germany |
| Westerstede | 26655 | Germany |
| Bari | Apulia | 70124 | Italy |
| Catanzaro | Calabria | 88100 | Italy |
| Bologna | Emilia-Romagna | 40139 | Italy |
| Trieste | Friuli Venezia Giulia | 34127 | Italy |
| Udine | Friuli Venezia Giulia | 33100 | Italy |
| Rome | Lazio | 00100 | Italy |
| Rome | Lazio | 00133 | Italy |
| Rome | Lazio | 00135 | Italy |
| Genoa | Liguria | 16147 | Italy |
| Cassina Nuova Di Bollate | Lombardy | 20021 | Italy |
| Gardone V.T. | Lombardy | 25063 | Italy |
| Milan | Lombardy | 20122 | Italy |
| Milan | Lombardy | 20127 | Italy |
| Milan | Lombardy | 21100 | Italy |
| Campobasso | Molise | 86100 | Italy |
| Bra | Piedmont | 12042 | Italy |
| Novara | Piedmont | 28100 | Italy |
| Cagliari | Sardinia | 09127 | Italy |
| Sassari | Sardinia | 07100 | Italy |
| Catania | Sicily | 95123 | Italy |
| Messina | Sicily | 98125 | Italy |
| Palermo | Sicily | 90129 | Italy |
| Florence | Tuscany | Italy |
| Perugia | Umbria | 06158 | Italy |
| Conegliano | Veneto | 31015 | Italy |
| Padova | Veneto | 35128 | Italy |
| Alcoy | Alicante | 3802 | Spain |
| Almería | Almeria | 4600 | Spain |
| Manacor | Balearic Islands | 07500 | Spain |
| Palma de Mallorca | Balearic Islands | 07014 | Spain |
| Barcelona | Barcelona | 08025 | Spain |
| Barcelona | Barcelona | 08830 | Spain |
| Terrassa | Barcelona | 08221 | Spain |
| Burgos | Burgos | 9006 | Spain |
| Santander | Cantabria | 39008 | Spain |
| Torrelavega | Cantabria | 39300 | Spain |
| Granada | Granada | 18003 | Spain |
| A Coruña | La Coruña | 15001 | Spain |
| Málaga | Malaga | 29010 | Spain |
| Pamploma | Navarre | 31014 | Spain |
| Pamplona | Navarre | 31008 | Spain |
| Palencia | Palencia | 34004 | Spain |
| Vigo | Pontevedra | 36214 | Spain |
| Langreo | Principality of Asturias | 33900 | Spain |
| Soria | Soria | 42005 | Spain |
| Reus | Tarragona | 43206 | Spain |
| Valencia | Valencia | 46010 | Spain |
| Valladolid | Valladolid | 47005 | Spain |
| Bilbao | Vizcaya | 48300 | Spain |
| Bilbao | Vizcaya | 48370 | Spain |
| Vitoria-Gasteiz | Vizcaya | 01004 | Spain |
| Belfast | BT12 6B | United Kingdom |
| Bristol | BS8 2BN | United Kingdom |
| Cambridge | CB2 0ST | United Kingdom |
| Cheshire | WA2 8WA | United Kingdom |
| Cornwall | TR15 2SP | United Kingdom |
| Coventry | CV1 4FH | United Kingdom |
| Essex | CO15 1LH | United Kingdom |
| Glasgow | G12 0XH | United Kingdom |
| Hemel Hempstead | HP3 8EH | United Kingdom |
| Lincolnshire | NG34 8GG | United Kingdom |
| Norfolk | NR1 3RE | United Kingdom |
| Nottingham | NG3 6AA | United Kingdom |
| Stoke-on-Trent | ST4 6TH | United Kingdom |
| Walsall | WS2 9SS | United Kingdom |
| Wolverhampton | WV14 0DQ | United Kingdom |
| Franklin M, Mukuria C, Mulhern B, Tran I, Brazier J, Watson S. Measuring the Burden of Schizophrenia Using Clinician and Patient-Reported Measures: An Exploratory Analysis of Construct Validity. Patient. 2019 Aug;12(4):405-417. doi: 10.1007/s40271-019-00358-x. |
| 30088146 | Derived | Domenech C, Bernasconi C, Moneta MV, Nordstroem AL, Cristobal-Narvaez P, Vorstenbosch E, Cobo J, Ochoa S, Haro JM. Health-related quality of life associated with different symptoms in women and in men who suffer from schizophrenia. Arch Womens Ment Health. 2019 Jun;22(3):357-365. doi: 10.1007/s00737-018-0896-0. Epub 2018 Aug 7. |
| ID | Term |
|---|---|
| D012559 | Schizophrenia |
| ID | Term |
|---|---|
| D019967 | Schizophrenia Spectrum and Other Psychotic Disorders |
| D001523 | Mental Disorders |
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