Efficacy of a Web-based Weight Loss Program

Is the Support of a Web-based Weight Loss Program Effective in Supporting Self-initiated Weight Loss and Lifestyle Changes?

Since overweight and obesity, a risk factor for various diseases, is a prevalent problem in the modern society, it is important to search for new strategies to counteract this. In contrast to in person support, the internet provides a low cost opportunity, which is able to reach a large part of the population. Therefore a web-based weight loss program may be an adequate mean for many people. Now it is hypothesised that a web-based weight loss program is able to support a reduction of body weight and weight-related cardiovascular risk factors effectively and to promote a healthier lifestyle. It is expected that program use, compared to a control group, results in greater reductions in body weight and cardiovascular risk.

Inclusion Criteria:

• age 30-65 years
• body Mass Index: 27-39,9 kg/m2
• ECOG-Performance status degree 0 or 1
• basal internet skills
• private internet access
• signed informed consent

Exclusion Criteria:

• malign diseases
• major organ diseases
• inflammatory bowel diseases
• insulin - dependent diabetes mellitus
• pregnancy, breast feeding
• treatment of eating disorders (e.g. bulimia, anorexia nervosa) within past 5 years
• parallel participation in other weight loss programs or other trials
• weight loss > 5% within past 6 month
• chronic therapy with glucocorticoids
• subjects treated because of psychiatric disorders (e.g. schizophrenia, bipolar disorder) in the past
• subjects with expected non-compliance to protocol guidelines