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The purpose of this study is to test the effectiveness of whole body periodic acceleration for helping with symptoms of aches and pains suffered by many patients.
This is an unblinded cross-over study of whole-body periodic acceleration (WBPA) to ascertain if this treatment modality provides symptomatic relief of pain, stiffness, and abnormal gait and balance in a variety of conditions. The study will compare a specific mechanism of motion, whole-body periodic acceleration (WBPA), that has been shown to increase the release of beneficial mediators from the vascular endothelium into the circulation, to a control condition of slow passive motion that promotes relaxation but does not increase release of beneficial mediators into the circulation. The study tests the efficacy and safety of a commercially available device that consists of a motion platform, called Exer-Rest©, that is capable of producing both types of motion to be tested. In this investigation, 15 subjects will be randomly assigned to either procedure for 10 treatments for 2 weeks followed by a one-week "wash-out" period. Then the opposite treatment will be employed for two weeks.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Whole body periodic acceleration (Exer-Rest) | Device | Lying on the vibrating bed for 45 minutes per session for 10 sessions over 2 weeks. |
| Measure | Description | Time Frame |
|---|---|---|
| Self-report of pain | Self-report of pain at start and completion of first course of treatment lasting for 2 weeks. | 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of life | Self-report of change in quality following 2 weeks of treatment. | 2 weeks |
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Inclusion Criteria:
Subjects qualifying for this study satisfy the following criteria:
Exclusion Criteria:
WBPA is contraindicated for subjects who are pregnant or who suffer with unexplained leg pain, skin eruptions, or who have unstable spinal injuries or conditions. Subjects who cannot tolerate the motion and duration of treatment are also excluded.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Translational Medicine Group | Recruiting | Bethesda | Maryland | 20852 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16236957 | Background | Sackner MA, Gummels E, Adams JA. Effect of moderate-intensity exercise, whole-body periodic acceleration, and passive cycling on nitric oxide release into circulation. Chest. 2005 Oct;128(4):2794-803. doi: 10.1378/chest.128.4.2794. |
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| ID | Term |
|---|---|
| D010146 | Pain |
| D051346 | Mobility Limitation |
| D001519 | Behavior |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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