Mesenchymal Stem Cells; Donor and Role in Management and Reconstruction of Nonunion Fracture

The investigators hypothesized that mesenchymal stem cells can be isolated from fracture site, iliac crest, and tibial crest, and can be expanded to be used in the management of nonunion fracture.

Inclusion Criteria:

• athropic nonunion fracture of the long bone

Exclusion Criteria:

• immunocompromise,
• active infection,
• pathological fracture,
• ongoing hormonal therapy