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The purpose of this study is to compare the quality of a transversus abdominis plane blockade with an intravenous pain therapy with opioids. Due to the relatively low side effect profile and comparably few contraindications, this method offers a good option, to be a standard procedure or better alternative in the treatment of pain in surgery of the prostate.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| general anesthesia and epidural catheter (control) | No Intervention | General anaesthesia
| |
| general anesthesia and regional anesthesia | Experimental | General anesthesia
|
|
| general anaesthesia and intravenous pain therapy | Experimental | General anaesthesia
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transversus abdominis plane blockade | Procedure | Bilateral one time injection of local anaesthetic in the space between the transversus abdominis muscle and obliquus internus muscle preoperatively. Follow up for three days. |
| Measure | Description | Time Frame |
|---|---|---|
| Pain in rest in the op-area | Pain in rest in the op-area during the first 3 days | 3 days |
| Measure | Description | Time Frame |
|---|---|---|
| Opioid consumption | opioidconsumption during the first 3 days | 3 days |
| Pain in motion in the op-area | Pain in the op-area in motion during the first three days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jürgen Birnbaum, MD | Charite, Department of Anesthesiology and Intensive Care, Campus Mitte, Universitätsmedizin Berlin | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Anaesthesiology and Intensive Care Medicine Campus Charitè Mitte, Charite Universitätsmedizin Berlin | Berlin | State of Berlin | 10117 | Germany |
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| ID | Term |
|---|---|
| D010146 | Pain |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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|
| Morphine-patient-controlled-analgesia-device | Procedure | Morphine-patient-controlled-analgesia-device for three days: 1mg/ml, Dosage 2mg bolus injection on demand every 10 minutes possible. |
|
| 3 days |
| Pain outside the op-area | Pain outside the op-area during the first three days | 3 days |
| Contentment with the pain therapy at all | Contentment with the pain therapy at all for the first three days | 3 days |
| Frequency of postoperative vomiting and nausea | Frequency of postoperative vomiting and nausea during the first three days | 3 days |
| Incidence of pruritus | Incidence of pruritus during the first three days | 3 days |
| Tenesmuses of the bladder | Tenesmus of the bladder during the first three days | 3 days |
| Contentment of the Patient at all | Contentment of the patient at all during the first three days | 3 days |