Comparison of Methotrexate (MTX) and the VIBEX™ MTX Device

Exposure, Safety and Local Tolerance Study Comparing the Relative Bioavailability of Oral Methotrexate and the VIBEX™ MTX Device in Adult Subjects With Rheumatoid Arthritis

Relative Bioavailability Comparison study

A Phase 2, Open-Label, Randomized, 3-Way Crossover Study to Compare the Relative Bioavailability of Oral Methotrexate and the VIBEX™ MTX Device in Adult Subjects With Rheumatoid Arthritis

Inclusion Criteria:

• Male or female patients ≥18 years of age, diagnosed with Rheumatoid Arthritis

Exclusion Criteria:

• Pregnant females
• Any other clinically significant disease or disorder which, in the opinion of the investigator might put the subject at risk