Transcranial Magnetic Stimulation in Treatment of Attention Deficit/Hyperactivity Disorders

Transcranial Magnetic Stimulation of the Pre-Frontal Cortex in the Treatment of Attention Deficit/Hyperactivity Disorders: A Randomized, Controlled, Double Blind Study.

• ADHD is one of the most common psychiatric disorders.
• While most of the attention is directed towards youth, 60% continue to suffer symptoms into adult life.
• Current treatment is effective, but 30% suffer side effects that lowers QOL, and 20% are non-responders.
• Known mechanism of pathophysiology includes hypoactive dopaminergic system, especially at right PFC.
• It is this study hypothesis that by stimulating the right PFC by TMS, it will be possible to alleviate ADHD symptoms.
• A 10 sessions of treatment will by applied on a randomly allocated group of patients, diagnosed with ADHD, in a 2:1 ratio: The first group will receive an actual TMS treatment, and the second group will receive a sham treatment.
• Improvement of objective and subjective ADHD scale will be examined.

Inclusion Criteria:

• Age 18-50
• Established diagnosis of ADHD
• No C/I for TMS
• Has signed an informed consent form

Exclusion Criteria:

• Major Psychiatric disorders (Psychotic or Affective)
• Active use of drugs (4 weeks prior to participation)
• Neurologic disorder such as Epilepsy.
• No use of stimulants during the previous 7 days