Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks

Value of Mifepristone in Eliminating the Need for a Second Set of Osmotic Dilators Prior to Dilation and Evacuation Between 19-24 Weeks: A Randomized Trial

A common practice for preparation for surgical abortion after 19 weeks gestation is the placement of multiple sets of osmostic dilators 1-2 days prior to the procedure. The investigators aim to study the addition of mifepristone as an adjunct to cervical dilation prior to abortion between 19-24 weeks gestation, and its potential to minimize the number of painful procedures and time in clinic (or away from work/home) that multiple sets of dilators can require. The investigators hypothesize that one set of dilators with mifepristone will result in similar procedure times and decreased "total" time as two sets of dilators.

Inclusion Criteria:

• >18 years old
• Viable, Singleton pregnancy
• Voluntarily seeking abortion between 19 and 24wks gestation
• Able to give informed consent and comply with study protocol
• Fluent in English or Spanish

Exclusion Criteria:

• Allergy to misoprostol or mifepristone