Optimum Misoprostol Dose Prior to Office Hysteroscopy

The Optimum Dose of Vaginal Misoprostol Prior to Office Hysteroscopy: Double Blind Randomized Controlled Trial

Misoprostol is an effective agent for cervical priming before office hysteroscopy, vaginal route is the best, optimum dose not yet known.

The investigators will compare between 2 different doses of vaginal misoprostol, group (1) 200 ug, group (2) 400 ug, 3hours prior to office hysteroscopy , Infertile patient, patients with abnormal bleeding and patient with recurrent abortion Outcome measure: pain score, easiness of the procedure, procedure time, complications

Inclusion Criteria:

• Female patient pre- or postmenopausal undergo office hysteroscopy.
• Age: from 20 to 60.
• BMI between 18 and 30.

Exclusion Criteria:

• PID or
• Heavy uterine bleeding
• Cervical malignancy.
• Symptoms suggestive of endometriosis .
• Any cervical abnormality such as pinhole cervix that would obviate passage of a catheter through the cervix.