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The aim of this study is to determine on preliminary basis weather an elevated pro-calcitonin level can be used to assess ischemia as a result of coronary artery complications during percutaneous coronary intervention (PCI).
Pro-calcitonin is a type of protein found in the blood. This protein has recently be found to be elevated in patients with diseases of the arteries of the heart such as heart attack.
Percutaneous coronary intervention (PCI) is widely used in the treatment of many patients with blockage in the arteries of the heart.
the investigators normally used a marker called troponin after cardiac catheterization. However, this marker may not be specific.
Pro-calcitonin has been found to be a useful marker for the detection of myocardial injury. the value of Pro-calcitonin as a marker for the identification of myocardial damage undergoing PCI has not yet been studied.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| coronary complication | patients with coronary complication and patients without coronary complications. pro-calcitonin will be measured in both groups to see if any correlation. |
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| Measure | Description | Time Frame |
|---|---|---|
| Pro-calcitonin blood level | "0,24 hours post cardiac intervention" |
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Inclusion Criteria:
Exclusion Criteria:
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Community sample
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| Name | Affiliation | Role |
|---|---|---|
| Habib Habib, MD | Saint Michael's Medical Center | Principal Investigator |
| Fayez Shamoon, MD,FACC | Saint Michael's Medical Center | Study Director |
| yaser elnhar, MD | Saint Michael's Medical Center | Study Chair |
| Vincent Debari, PhD | Saint Michael's Medical Center | Study Chair |
| Ashraf Jmeian, MD | Saint Michael's Medical Center | Study Chair |
| Ahmad Isbitan, MD | Saint Michael's Medical Center | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Saint Michael's Medical Center | Newark | New Jersey | 07102 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21378450 | Background | Sinning CR, Sinning JM, Schulz A, Schnabel RB, Lubos E, Wild PS, Papassotiriou J, Bergmann A, Blankenberg S, Munzel T, Bickel C; AtheroGene Study Investigators. Association of serum procalcitonin with cardiovascular prognosis in coronary artery disease. Circ J. 2011;75(5):1184-91. doi: 10.1253/circj.cj-10-0638. Epub 2011 Mar 3. |
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| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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