Hyperbaric Oxygen - a New Treatment Modality in Patients With Radiation Damaged Salivary Gland Tissue

Hyperbaric Oxygen - a New Treatment Modality in Patients With Radiation Damaged Salivary Gland Tissue.

Randomized clinical trial regarding the effect of hyperbaric oxygen on late radiation tissue injury to salivary gland tissue.

Inclusion Criteria

• Head and neck cancer with planned radiation therapy
• Age > 18 years

Exclusion Criteria:

• Surgical treatment of head and neck cancer
• Salivary gland disease
• Severe claustrophobia
• Pregnancy or lactation (fertile women must use safe contraceptives)
• Uncontrolled hypertension (> 220/110)
• Epilepsy
• Lack of ability to equalize inner ear pressure
• Pneumothorax
• Thoracic surgery within one month before HBO treatment
• Abuse of alcohol, drugs or narcotics
• Exposed titanium surfaces or defect titanium in the oral cavity
• Previous HBO treatment