Study of Stress and Life Quality of Patients Participating in Clinical Trials Versus Patients Non Participating

Psychological and Emotional Impacts of Participation in Oncologic Clinical Trials

This study aims to assess anxiety/depression and life quality of patients included in clinical trials versus patients treated in a standard way.

This study aims to assess anxiety/depression and life quality of patients included in clinical trials versus patients treated in a standard way A case-control study

Inclusion Criteria:

• patient with solid tumor or recurrent hematologic cancer, treated by chemotherapy or targeted therapy evaluated every 2 or 3 cycles; except for clinical trials associating non drug treatment (radiotherapy, surgery...)

• subject to a 1st, 2nd or 3rd line of antitumor treatment

  • a phase 2 open labeled study,
  • a phase 2 or 3 blind randomised study,
  • a phase 2 or 3 open randomised study,
  • a standard treatment non participating to a clinical trial

• male or female patients ≥ 18 years of age

• karnovsky ≥ 70 % or WHO (Performance Status) ≤ 2

• recovered from prior toxicities

• social security covered

• written informed consent given

Exclusion Criteria:

• psychiatric disorders, receiving psychotropic treatment
• physical or psychological issues
• forbidden to be included in this study