Tissue Sparing Therapy of Female Precancerous Genital Lesions With VITOM

Development of a Tissue Sparing Procedure for the Diagnosis and Therapy of Female Precancerous Genital Lesions Combining Endoscopic and Ultrasound Technics.

Object of the study is the evaluation of the use of a rigid laparoscope for the diagnosis and therapy of lesions of the female genital tract as a substitution or a complementary method to colposcopy with the development of new standards for a tissue sparing therapy Use of existing laparoscopic instruments, which allow a better quality level in the diagnosis and therapy than the current routine.

Development of new optics and instruments, which allow a tissue sparing approach Pre and postoperative measurement of the cervical volume, to be sure that the tissue removal is kept to a minimum level Development of qualitaty parameters for the most tissue respecting operations of the uterine cervix Prospective evaluation of the influence of tissue sparing surgery on future pregnancies

Inclusion Criteria:

• Karnowsky-Index > 80,
• 18-80 years,
• CIN.

Exclusion Criteria:

• Pregnancy,
• Previous or current cancer,
• Radio therapy of the pelvis,
• Serious internistic accompanying diseases,
• Psychiatric diseases,
• HIV infection,
• Drug addiction.