Perioperative Magnesium Sulphate as a Cerebral Protector in Neurosurgical Patients

Perioperative Magnesium Sulphate as a Cerebral Protector in Neurosurgical Patients

The purpose of this study is to determine the relationship between magnesium sulphate administration and levels of S100B protein in serum of patients undergoing supratentorial brain parenchymal resection.

Inclusion Criteria:

• Male and females older than 18 years.
• Undergoing supratentorial parenchyma resection surgery.
• Capable of collaborate on probes and explorations included in the study.
• Signature the written informed consent form.

Exclusion Criteria:

• Life expectancy less than 12 months due to the suspected histological type of tumour.
• Hypothalamic-pituitary axis illness.
• Presence of Melanoma previously.
• Glomerular filtration rate less than 60 mL/min.
• Thyroid or parathyroid glands pathology.
• Myasthenia gravis.
• Respiratory depression.
• Pregnancy or breastfeeding.