Unknown statusInterventionalNot ApplicableLast updated May 16, 2012

N-Acetylcysteine for Patients With COPD and ChronicBronchitis

Effects of High-Dose N-Acetylcysteine on Respiratory Health Status in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Chronic Bronchitis: A Randomized, Placebo-Controlled Trial-1

Overview

ClinicalTrials.gov ID: NCT01599884
Lead Sponsor: Center for Veterans Research and EducationOTHER
Brief Summary: N-acetylcysteine (NAC) is described as having mucolytic and antioxidant properties. It is widely prescribed for patients with chronic obstructive pulmonary disease (COPD), particularly for those who have accompanying symptoms of chronic cough and sputum production. Randomized, placebo controlled indicate that it is safe and that it may have some clinical benefit when used at relatively low doses. It is postulated that substantially higher doses of NAC will be well-tolerated and will provide better symptom control while also decreasing blood makers of oxidant stress and inflammation.

Status

Overall Status: Unknown status
Start Date: Jun 2012
Primary Completion Date: May 2013Estimated
Completion Date: Aug 2013Estimated

Study Record Dates

First Submitted: May 15, 2012
First Submitted that Met QC Criteria: May 15, 2012
First Posted: May 16, 2012Estimated
Last Update Submitted that Met QC Criteria: May 15, 2012
Last Update Posted: May 16, 2012Estimated
Last Verified: May 2012

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