Comparison of Two Omeprazole-Containing Products for Relief of Frequent Heartburn (MK-0764A-036)

Protocol PT 11-29: Randomized, Open-label, Cross-over Pilot Study to Evaluate and Compare Two Omeprazole Containing Products for Relief of Frequent Heartburn

This study will evaluate a single ingredient product (omeprazole 20 mg) with a combination product capsule (omeprazole 20 mg + sodium bicarbonate 1100 mg) in participants with frequent heartburn.

Inclusion Criteria:

• Females of reproductive potential must demonstrate a negative urine pregnancy test and agree to use an acceptable method of birth control
• Suffer from frequent heartburn
• Refrain from taking non-study medicine or treatment for heartburn for the duration of the study
• Be free of any clinically significant disease that requires a physician's care
• Read and understand English

Exclusion Criteria:

• Any significant medical condition which is a contraindication to the use of omeprazole or sodium bicarbonate
• Known hypersensitivity to the study drugs or any components
• Experiencing any of the following: trouble or pain with swallowing food, vomiting with blood, bloody or black stools
• Participation in another investigational study within 4 weeks prior to the screening visit.