Clinical Trials With a Local Anesthetic Lozenge for the Treatment of Chronic Oral Pain

Clinical Trials With a Local Anesthetic Lozenge for the Treatment of Oral Mucosal Pain in Burning Mouth Syndrome, Sjögrens Syndrome and Lichen Planus.

The aim of the project is to do a fase two trial, where the effect of a local anesthetic lozenge will be tested in regard to oral pain, dryness of the mouth, irregularity of taste as well as investigate a potential antiinflammatory effect in patients with burning mouth syndrome, Sjögrens syndrome and lichen planus.

Inclusion Criteria:

• Diagnosed with burning mouth syndrome, Sjögrens syndrome or lichen planus
• All fertile women need to use save contraception
• Age between 18 and 75 years
• Able to speak, read and understand the danish language
• Must be informed orally and release a written consent and a signed authorization statement

Exclusion Criteria:

• Pregnant or breastfeeding women
• Known allergy to bupivacaine or other local anesthetics of the amide type
• Active infection which requires antibiotic treatment
• Patients in immune suppressive treatment