Effects of Convective Therapies in Dialysis Patients

Effects of Convective Therapies in Dialysis Patients

Convective therapies have been proposed for improving chronic dialysis patient outcomes, including intradialytic symptomatic hypotension.

To evaluate the frequency of sessions with intradialytic symptomatic hypotension in different types and doses of convective therapies compared with low-flux hemodialysis (HD), the investigators performed a multicentre, open-label, randomized controlled trial.

Inclusion Criteria:

• Dialysis patients aged 18-80 years
• thrice-weekly HD or HDF for at least 6 months
• body weight less or equal to 90 Kg
• stable clinical condition
• written consent

Exclusion Criteria:

• infections
• malignancies
• active systemic diseases
• active hepatitis or cirrhosis
• unstable diabetes
• diuresis higher than 200 ml/24h
• dysfunction of vascular access
• blood flow rate less than 300 ml/min