The purpose of this study is to determine if a sizable myocardial infarction (heart attack) results in negative changes to renal structure and function (i.e. has a negative impact on the kidneys).

To determine if the renal response to a myocardial infarction is a predictor of the patients future health.

Chronic heart and kidney disease are increasingly common in Western society. Both conditions are associated with frequent hospitalisation and increased mortality. Furthermore, there are mechanistic reasons why one condition may beget the other; the so-called "cardiorenal syndrome". The investigators therefore wish to determine if a sizable myocardial infarction (heart attack) results in negative changes to renal structure and function (i.e. has a negative impact on the kidneys). The investigators also wish to determine if the renal response to a myocardial infarction is a predictor of the patients future health. To do this the investigators will measure markers of kidney function at the time of the heart attach, at discharge, 1 month, 6 months and 12 months and correlate this with the patients clinical condition.

Inclusion Criteria:

Age > 18 years

Have provided written informed consent

Group 1:

• Non-Q wave MI patients
• normal cardiac and renal function
• No use of contrast
• eGFR > 60ml/min

Group 2:

• Patients undergoing coronary angiography +/- PCI for stable CAD or non-Q wave MI
• normal cardiac and renal function
• eGFR > 60ml/min

Group 3:

• Acute STEMI Full thickness infarct (STEMI)
• eGFR ≥ 60ml/min

Group 4:

• Acute STEMI Full thickness infarct (STEMI)
• eGFR < 60ml/min

Exclusion Criteria:

• Unable or unwilling to comply with the study protocol
• Underlying medical condition which, in the opinion of the investigator, will effect the safely or efficacy of the study

Patients who have presented to the Emergency Department with chest pain caused by a possible myocardial infarction.