The objective of this study is to assess the safety and efficacy of Oliclinomel N4 compared to compounded ternary parenteral nutrition (PN) admixtures for the delivery of PN in hospitalized adults for whom oral or enteral nutrition is not possible, insufficient, or contraindicated.

Inclusion Criteria:

• Inpatient but hospitalized < 14 days prior to enrollment
• Requires PN because oral or enteral nutrition is not possible, insufficient, or contraindicated
• Has capability to complete at least 5 days of study treatment (i.e., PN)
• Has a useable peripheral vein for delivery of intravenous (IV) PN

Exclusion Criteria:

• Has a life expectancy of < 6 days from initiation of study treatment, in the opinion of the Investigator
• Known hypersensitivity to the components of either of the investigational study treatments
• Use of prohibited medications (e.g. glucocorticosteroids or antitumor chemotherapeutic agents) within 30 days prior to enrollment
• Known serious clinically significant condition that would preclude participation in the study
• Known chronic active hepatitis, elevated liver function tests
• Known history of human immunodeficiency virus infection
• Known severe dyslipidemia, severe hyperglycemia,clinically significant abnormalities of plasma electrolytes
• Known pregnancy or lactation