Detection of Immune Changes as a Result of Surgical Trauma in Human Subject

Detection of Immune Changes as a Result of Surgical Trauma in Human Subject

Surgical trauma triggers a massive inflammatory response. Over time, both the innate and adaptive branches of the immune system are affected by surgical trauma. The purpose of this study to characterize the cellular and molecular mechanisms immune response to surgical trauma. Additionally, detailed information about patients' recovery profile will be recorded over a period of 6 weeks, with the eventual goal of linking immune responses to recovery profiles.

Inclusion Criteria:

• 18 - 90
• Planning to undergo hip surgery
• Fluent in English
• Willing and able to sign informed consent and HIPAA authorization

Exclusion Criteria:

• Any systemic disease that might compromise the immune system
• Diagnosis of cancer within the last 5 years
• Psychiatric, immunological, and neurological conditions that would interfere with the collection and interpretation of study data
• Pregnancy
• Any other conditions that, in the opinion of the investigators, may compromise a participant's safety or the integrity of the study