Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Institut für Sportwissenschaften, Frankfurt | UNKNOWN |
| Fresenius University of Applied Science | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this randomized controlled two-part study examines the effects of a structured sports intervention before, during and after hematopoetic stem cell transplantation (hsct) in children and adolescents.
The main aspects in the sports groups are resistance, endurance and flexibility training. The control group performs a mental training as well as relaxation exercises.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sport | Experimental |
| |
| Control | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise | Other | Supervised exercise training (aerobic, resistance, flexibility), 5 times per week |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Muscle strength | Upper limb: hand grip strength with JAMAR dynamometry; Lower limb: maximal isometric voluntary strength of M. quadriceps femoris | change between hospital admission and discharge (approximately 4-6 weeks) and 3 months and 6 months after transplantation |
| Measure | Description | Time Frame |
|---|---|---|
| Fatigue | Pediatric Quality of Life Inventory (PedsQL) | change between hospital admission and discharge (approximately 4-6 weeks) and 3 months and 6 months after transplantation |
| Biomarker in blood |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Children's Hospital | Frankfurt am Main | Hesse | 60590 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31089282 | Derived | Senn-Malashonak A, Wallek S, Schmidt K, Rosenhagen A, Vogt L, Bader P, Banzer W. Psychophysical effects of an exercise therapy during pediatric stem cell transplantation: a randomized controlled trial. Bone Marrow Transplant. 2019 Nov;54(11):1827-1835. doi: 10.1038/s41409-019-0535-z. Epub 2019 May 14. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
Not provided
Not provided
| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Mental Training |
| Other |
Memorial/ mental training and relaxation, 5 times per week |
|
Hematological and immunological reconstitution
| daily |
| Body composition | Bioelectrical Impedance Analyse (BIA; Data Input GmbH) | one time per week and change between 3 months and 6 months after transplantation |
| Endurance performance | 6-Minute-Walking-Test (6MWT); Ergospirometry and Echocardiography | change between hospital admission and discharge (approximately 4-6 weeks) and 3 months and 6 months after transplantation |