Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting

Efficacy of Two Different Pre-Intervention Therapeutic Strategies With Clopidogrel and Atorvastatin for the Prevention of Cerebral Damage During Carotid Artery Stenting. Armyda-Caro Randomized Trial.

The purpose of this study is to evaluate the efficacy and safety of two different loading doses of Clopidogrel and a reloading of Atorvastatin in the prevention of periprocedural ischemic brain damage in patients undergoing carotid angioplasty.

Inclusion Criteria:

• symptomatic and asymptomatic patients with finding of significant carotid stenosis

Exclusion Criteria:

• patients with acute injuries to the baseline MRI of the brain,
• patients with active bleeding,
• contraindications to statin therapy and MRI contraindications (pacemaker/claustrophobic).