Genetic Influences on Statin Blood Concentrations in African Americans

An Observational Study Investigating Genetic Influences on Statin Plasma Concentrations in Adult African American Patients

This study intends to determine the effects of genetic polymorphisms on statin response and daily systemic exposure (24-hour area under the time-concentration curve) of statins in African-American patients.

Inclusion Criteria:

• African-American patients taking a statin metabolized by CYP3A (e.g., atorvastatin, simvastatin, or lovastatin)

Exclusion Criteria:

• Age less than 18 years