Low Volume PEG With Low Residue Test Meals Versus High Volume Split-dose PEG Bowel Preparation

Efficacy and Tolerability of Morning (AM) Only Low Volume (2L) PEG With Low Residue Test Meals Versus High Volume (4L) Split-dose (PM/AM) PEG Bowel Preparation With Standard Meals: A Prospective Randomized, Investigator Blinded Trial

Morning only low volume PEG with low reside meals may enhance patient tolerability and have similar bowel cleansing efficacy compared to standard method using high volume split-dose PEG with standard diet.

We aimed to evaluate the efficacy and tolerability of bowel preparation protocols with low volume PEG and low residue meals PEG compared to conventional high volume (4L) split-dose and standard diet.

Entry criteria: Entry criteria: Adult outpatients and inpatients (18-85 years of age) who undergo colonoscopy for screening, cancer surveillance or with gastrointestinal symptoms, other symptoms

Primary Outcome: Quality of bowel preparation (Ottawa scale) Secondary Outcome: Tolerability (preparation completion, side effect), acceptance, willingness

Inclusion Criteria:

• Adult outpatients and inpatients (18-85 years of age) who undergo colonoscopy for screening, cancer surveillance or with gastrointestinal symptoms, other symptoms

Exclusion Criteria:

• Age under 18 years
• Pregnancy
• Breast feeding
• Prior history of surgical large bowel resection
• Severe medical condition such as severe cardiac
• Hepatic, renal failure (creatinine ≥ 3.0mg/dL (normal 0.8-1.4))
• Drug addiction or major psychiatric illness
• Suspected bowel obstruction or ileus
• Allergy to PEG
• Refusal of consent to participate in the study.