MR Characterisation/Localisation of Breast Cancer

Using Magnetic Resonance Techniques to Improve the Characterisation and Localisation of Breast Cancer

Objective: To determine the accuracy of multi-functional magnetic resonance (MR) in detecting, localising and characterising satellite lesions in relation to an index breast tumour in order to improve definition of clinical target volume after local excision.

Hypothesis: Pre-operative multi-functional MR has high sensitivity and specificity for localising unsuspected multifocal and multicentric lesions in women diagnosed with early breast cancer.

Inclusion Criteria:

• Biopsy proven invasive ductal carcinoma of the breast
• Unifocal disease
• Patient proceeding to mastectomy

Exclusion Criteria:

• Multifocal disease
• Previous surgery to ipsilateral breast
• Neoadjuvant chemotherapy
• Ferromagnetic implants
• Claustrophobia
• Cup size DD or greater