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This study is designed to compare the infection rates in wounds irrigated with sterile normal saline to those irrigated with chlorinated tap water. The hypothesis is that the wound infection rate subsequent to irrigation with tap water is not significantly different than the infection rate for wounds irrigated with sterile normal saline.
Inclusion criteria are patients older than 1-year of age who present to the emergency department with a soft-tissue laceration requiring repair. Exclusion criteria include patients with any underlying immunocompromising illness, current use of antibiotics, puncture or bite wounds, underlying tendon or bone involvement, or wounds more than nine hours old.
Patients are randomized to have their wounds irrigated either with tap water or sterile normal saline prior to closure, controlling for the volume and irrigation method used. Structured follow-up is completed at 48 hours and 30 days to determine the presence of infection.
The primary outcome measure is the difference in wound infection rates between the two randomized groups.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| wounds irrigated with sterile normal saline | Other | Patients in this arm had their wounds irrigated with sterile normal saline |
|
| wound irrigation with tap water | Other | Patients in the arm had their wounds irrigated with tap water |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| wound irrigation with study fluid | Procedure | wounds were either irrigated with sterile normal saline or tap water. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Wound Infection at 48 hours | The primary outcome for this study is the difference in wound infection rates between the two randomized groups. It is assessed at 48 hours | 48 hours |
| Measure | Description | Time Frame |
|---|---|---|
| wound infection manifest at 30 days | patients are again contacted at 30 days after repair of their wound to assess for evidence of delayed or late infections | 30 days |
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Inclusion Criteria:
• Patients older than 1-year of age, who presented to the ED with an uncomplicated soft-tissue laceration requiring repair.
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Stanford University Medical Center | Stanford | California | 94305 | United States |
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| ID | Term |
|---|---|
| D014946 | Wound Infection |
| ID | Term |
|---|---|
| D007239 | Infections |
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