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The primary purpose of this study is to estimate the relative bioavailability and food effect of a PF-05089771 tablet.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PF-05089771 Oral Dispersion fasted | Experimental | Oral dispersion TS formulation- fasted |
|
| PF-05089771 TS formulation fasted | Experimental | Tablets TS formulation- fasted |
|
| PF-05089771 TS formulation fed | Experimental | Tablets TS formulation- fed |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PF-05089771 | Drug | Oral dispersion TS formulation- fasted |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Maximum concentration (Cmax) for PF-05089771 in plasma (measured in ng/mL) | days 1-3 | |
| AUClast = Area under the curve from the time of dosing to the last data point taken (ng.hr/mL) | days 1-3 | |
| AUCinf = Area under the curve from the time of dosing extrapolated to infinity (ng.hr/mL) | days 1-3 | |
| Tmax = Time of maximum concentration of PF-05089771 in plasma (hr) | days 1-3 | |
| t½ = Elimination half life of PF-05089771 (hr) | days 1-3 |
| Measure | Description | Time Frame |
|---|---|---|
| evaluation of safety clinical laboratory tests, vital signs, ECGs, physical examinations and adverse event monitoring. | days 1-3 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Pfizer CT.gov Call Center | Pfizer | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pfizer Investigational Site | Brussels | B-1070 | Belgium |
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| Label | URL |
|---|---|
| To obtain contact information for a study center near you, click here. | View source |
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| ID | Term |
|---|---|
| D010146 | Pain |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| C000618268 | PF-05089771 |
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| PF-05089771 |
| Drug |
Tablets TS formulation- fasted |
|
| PF-05089771 | Drug | Tablets TS formulation- fed |
|