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The investigators are comparing two standard of care procedures which can be performed at the same time, or sequentially. The hypothesis being tested is whether simultaneous release of both the carpal Tunnel and the Pronator Teres results in a better outcome in terms of symptom relief and recurrence than Carpal Tunnel Release alone when signs and symptoms of both carpal tunnel and pronator Teres syndromes are present.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Carpal Tunnel and Pronator Teres Release | Active Comparator | Patients enrolled in this arm of the study will have both surgical procedures performed at the same time |
|
| Carpal Tunnel Release only | Active Comparator | Patients enrolled in this arm will have only Carpal Tunnel Release performed. In they still have symptoms of median nerve neuropathy, they will be scheduled for an additional procedure to release the pronator Teres in a separate surgery. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pronator Teres Release | Procedure | Surgical release of median nerve compression |
|
| Measure | Description | Time Frame |
|---|---|---|
| Symptom severity and functional status score (Brigham and Women's Carpal Tunnel Questionnaire) | The primary outcome measure will be the difference between the pre and post operative assessments of the questionnaire, which will represent the degree of improvement as result of the surgical intervention. | 12 months |
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Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Tuna Ozyurekoglu, MD | Contact | 502-561-4263 | tozyurekoglu@cmki.org | |
| Millicent L Horn, BS | Contact | 502-562-0307 | mhorn@cmki.org |
| Name | Affiliation | Role |
|---|---|---|
| Tuna Ozyurekoglu, MD | Christine M. Kleinert Institute for Hand and Microsurgery | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Christine M. Kleinert Institute for Hand and Microsurgery | Recruiting | Louisville | Kentucky | 40202 | United States |
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| dual compression release | Procedure | Both the carpal tunnel compression and the pronator teres compression will be released on the same day. |
|
| dual compression release | Procedure | both procedures will be done on the same day |
|
| median nerve release only | Procedure | only the carpal tunnel compression is released |
|
| ID | Term |
|---|---|
| D002349 | Carpal Tunnel Syndrome |
| ID | Term |
|---|---|
| D020423 | Median Neuropathy |
| D020422 | Mononeuropathies |
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D009422 | Nervous System Diseases |
| D009408 | Nerve Compression Syndromes |
| D012090 | Cumulative Trauma Disorders |
| D013180 | Sprains and Strains |
| D014947 | Wounds and Injuries |
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