This is the first study focused on features/stereotypes of the first and second-line treatment patterns in Russia, comparison of different treatments, and determination of effective hormone treatment patterns in real-life practice with evaluation of pharmacoeconomic aspects. Study LINE is designed for collection of data on clinical effectiveness of second-line hormone treatment and quality of life in patients with breast cancer(BC).

LINE: Treatment patterns in postmenopausaL women wIth hormone receptor positive breast caNcEr

Inclusion Criteria:

• Postmenopausal women with hormone receptor-positive breast cancer:
• Recurrence after the adjuvant hormone therapy;
• Or initially inoperable locally advanced or metastatic breast cancer progressed after the first line hormone therapy;
• Ability to read and write and complete questionnaires Provision of written informed consent
• Patients who have already been prescribed therapy with the above-mentioned lines and who can continue on the prescribed therapy in the investigator's opinion according to his/her regular clinical practice and cure

Exclusion Criteria:

• As per study design, to ensure high validity of data and to obtain accurate information on real-life practice,
• Patients currently participating in other clinical studies will not be included in this study

hormone positive, postmenopausal breast cancer