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| ID | Type | Description | Link |
|---|---|---|---|
| ANW_20110816 | Other Identifier | Arthritis Northwest |
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| Name | Class |
|---|---|
| Bristol-Myers Squibb | INDUSTRY |
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The purpose of this study is to assess the effectiveness of Abatacept in real-world clinical practice. The main hypothesis to be examined in this study is, "Abatacept's effectiveness results in a single real-world clinic (n = 100) are reproducible at another site (n ~= 200)".
Two secondary hypotheses that will be tested are:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| All patients | All patients in T3 who have used Abatacept for at least 3 months between 2009-03-17 and 2011-11-30. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Abatacept | Drug | As prescribed by a doctor for patient medical care. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Determine the efficacy of abatacept by analyzing the change in CDAI, DAS28, and RAPID3 scores. | Change from baseline in CDAI, DAS28, and RAPID3 scores at approximately 6 months. |
| Measure | Description | Time Frame |
|---|---|---|
| Determine the efficacy of abatacept by analyzing the change in CDAI, DAS28, and RAPID3 scores. | Change from baseline in CDAI, DAS28, and RAPID3 scores at approximately 3 months. | |
| Determine the efficacy of abatacept by analyzing the change in CDAI, DAS28, and RAPID3 scores. |
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Inclusion Criteria:
Exclusion Criteria:
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All rheumatoid arthritis patients from a single site who have been on Abatacept for greater than 3 months.
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| Name | Affiliation | Role |
|---|---|---|
| Keith Knapp, Ph.D. | Arthritis Northwest PLLC | Study Director |
| Gary Craig, M.D. | Arthritis Northwest PLLC | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Arthritis Northwest | Spokane | Washington | 99208 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Background | Michael Schiff, Coralie Poncet, and Manuela Le Bars International Journal of Clinical Rheumatology 2010 5:5, 581-591 | ||
| 18793006 | Background | Pincus T, Swearingen CJ, Bergman M, Yazici Y. RAPID3 (Routine Assessment of Patient Index Data 3), a rheumatoid arthritis index without formal joint counts for routine care: proposed severity categories compared to disease activity score and clinical disease activity index categories. J Rheumatol. 2008 Nov;35(11):2136-47. doi: 10.3899/jrheum.080182. Epub 2008 Sep 15. |
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| ID | Term |
|---|---|
| D001172 | Arthritis, Rheumatoid |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
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| ID | Term |
|---|---|
| D000069594 | Abatacept |
| ID | Term |
|---|---|
| D018796 | Immunoconjugates |
| D000906 | Antibodies |
| D007136 | Immunoglobulins |
| D012712 | Serum Globulins |
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| Change from baseline in CDAI, DAS28, and RAPID3 scores at approximately 9 months. |
| D003240 |
| Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D001798 |
| Blood Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
| D005916 | Globulins |