VolulyteTM in Cardiac Surgery

Efficacy and Safety of Perioperative Infusion of 6 % Hydroxyethyl Starch 130/0.4 in an Isotonic Electrolyte Solution (VolulyteTM) vs. 5% HSA as Volume Replacement Therapy During Cardiac Surgery for Adult Patients

The study will compare the efficacy and safety of VolulyteTM and human albumin in elective open-heart surgery in adult patients.

Inclusion Criteria:

• male or female adult patients
• undergoing primary elective cardiac surgery applying extracorporeal circulation
• signed written informed consent

Exclusion Criteria:

• known contraindication against scheduled medication
• pre-operative acute normovolaemic haemodilution or preoperative autologous blood donation
• planned systemic hypothermia (body temperature < 30°C)
• expected time on ECC ≥ 2 hours