The Microcirculation in Acute Myocardial Infarction (Micro-AMI)

The Microcirculation in Acute Myocardial Infarction (Micro-AMI)

This study investigates the association between the microvascular resistance at the time of primary percutaneous intervention, with microvascular obstruction on CMR and blood markers of myocardial damage.

Inclusion Criteria:

• >18 years old
• Cardiac symptoms of > 20 mins chest pain or equivalent.
• ECG criteria consistent with STEMI (STEMI)
• Proceeding with percutaneous angioplasty
• Assent/ consent to the study

Exclusion Criteria:

• Known allergy to adenosine or gadolinium
• Chronic atrial fibrillation
• Renal impairment with eGFR <30
• Contraindication to angiography
• Contraindication to CMR (implanted pacemaker/ defibrillator, ferromagnetic metal implant/ injury, claustrophobia, obesity/ too large for CMR scanner)
• Cardiogenic shock
• Patients with special communication needs or altered consciousness.
• Patients who do not give assent/consent to the study