Postoperative Sleep Disturbances After Zolpidem Treatment in Fast-track Hip and Knee Replacement

Postoperative Sleep Disturbances After Zolpidem Treatment in Fast-track Hip and Knee Replacement

Sleep after surgery has been found to be very distrubed immediately after major surgery. This is also seen after fast-track hip and knee replacement with length of stay of less than 3 days. Disturbed sleep has many adverse effects i.e. fatigue, possible hyperalgesia and decline in cognitive abilities.

Inclusion Criteria:

• Total hip or knee replacement in fast-track setup
• Age 60 years or above
• ASA class 1-3

Exclusion Criteria:

• Anesthesia within the pas 30 days
• Daily use of alcohol > 21 units / week
• Use of anxiolytics or hypnotics within the past 30 days
• Inability to read and understand Danish
• Marked reduction of sight or hearing
• Parkinson's disease or other neurological disaese causing function deficits
• Inability to cooperate to sleep monitoring
• allergy to the drug tested