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Several methods have been demonstrated to improve intubating conditions during sevoflurane induction in children. These include opioids, propofol, and addition of neuromuscular blocking agents in pediatric patients. But the study about the comparison of these agents has been uncommon. Frenectomy is common procedure to treat ankyloglossia. It is a short procedure performed under general anesthesia. The investigators aimed to compare intubating conditions among children with propofol, alfentanil or rocuronium after sevoflurane induction.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Propofol group | Active Comparator | Intravenous administration of propofol 2 mg/kg before intubation |
|
| Alfentanil group | Active Comparator | Intravenous administration of alfentanil 14 μg/kg before intubation |
|
| Rocuronium group | Active Comparator | Intravenous administration of rocuronium 0.3 mg/kg before intubation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| administration of propofol | Drug | intravenous administration of propofol 2 mg/kg before intubation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Intubating condition | The investigators will perform the evaluation of intubating condtion through scoring system provided by Viby-Mogensen during intubation procedure. The scoring system is consisted of excellent, good, and poor. | Participants will be followed for the duration of intubation, an expected average of 1 minute. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Severance hospital | Seoul | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33993571 | Background | Park S, Kim JH, Bae JC, Lee JR, Kim MS. Tracheal intubation with or without a neuromuscular blocking agent for a short surgical procedure in children: Prospective, randomized, double-blind trial. Paediatr Anaesth. 2021 Aug;31(8):863-870. doi: 10.1111/pan.14205. Epub 2021 Jun 3. |
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| administration of alfentanil | Drug | intravenous administration of alfentanil 14 μg/kg before intubation |
|
| administration of rocuronium | Drug | Intravenous administration of rocuronium 0.3 mg/kg before intubation |
|
| ID | Term |
|---|---|
| D000072676 | Ankyloglossia |
| ID | Term |
|---|---|
| D009057 | Stomatognathic Diseases |
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