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| ID | Type | Description | Link |
|---|---|---|---|
| 2011-A01059-32 | Other Identifier | RCB number |
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This research project consists of a prospective diagnostic study conducted on patients with clinical suspicion of rhabdomyolysis admitted to the emergency rooms of the University Hospitals of Nimes, Montpellier, Paris, Nice and Toulon Inter Army Hospital. The main objective of this study is to determine whether the plasma level of Neutrophil Gelatinase Associated Lipocalin (NGAL) may be retained as a predictor of acute renal failure (ARF) occurring within 48 hours after admission for rhabdomyolysis.
The secondary objectives of this are:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients | Adult patients with suspected rhabdomyolysis admitted to the participating University Hospital emergency rooms (see inclusion/exclusion criteria). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Plasma NGAL level | Biological | The plasmatic level of Neutrophil Gelatinase Associated Lipocalin is measured in ng/ml/ |
|
| Measure | Description | Time Frame |
|---|---|---|
| Plasma NGAL level | ng/ml | Admittance to the ermergency room (ie at baseline) |
| Measure | Description | Time Frame |
|---|---|---|
| Delay between initiation of treatment and beginning of acute renal failure | meaured in hours | Day 2 |
| Delay between cause and treatment | Hours elapsed between proposed cause of rhabdomyolysis and treatment initiation measured in hours. |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients with suspected rhabdomyolysis admitted to the participating University Hospital emergency rooms (see inclusion/exclusion criteria).
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| Name | Affiliation | Role |
|---|---|---|
| Stéphane Pommet, MD | Centre Hospitalier Universitaire de Nīmes | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Nîmes - Hôpital Universitaire Carémeau | Nîmes | Gard | 30029 | France | ||
| CHU de Montpellier - Hôpital Lapeyronie |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39551581 | Result | Pommet S, Coisy F, Demattei C, Balaguer L, de Bauwere DP, Grau-Mercier L, Markarian T, Bobbia X, Genre Grandpierre R. Does serum neutrophil gelatinase-associated lipocalin level predict acute kidney injury in patients with acute rhabdomyolysis in the emergency department? A multicentre prospective study. BMJ Open. 2024 Nov 17;14(11):e088859. doi: 10.1136/bmjopen-2024-088859. |
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| ID | Term |
|---|---|
| D012206 | Rhabdomyolysis |
| D058186 | Acute Kidney Injury |
| D004630 | Emergencies |
| ID | Term |
|---|---|
| D009135 | Muscular Diseases |
| D009140 | Musculoskeletal Diseases |
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
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| Day 2 |
| Need for extracorporeal blood purification | yes/no | Hospital discharge (expected average of 2-3 days) |
| Patient admitted to ICU? | yes/no | Hospital discharge (expected average of 2-3 days) |
| Length of hospitalization | measured in days | Hospital discharge (expected average of 2-3 days) |
| Patient deceased during hospitalization | yes/no | Hospital discharge (expected average of 2-3 days) |
| Montpellier |
| 34295 |
| France |
| CHU de Nice - Hôpital St-Roch | Nice | 06006 | France |
| APHP - Groupe Hospitalier Pitié-Salpetrière | Paris | 75651 | France |
| Hôpital Interarmées Sainte Anne | Toulon | 83800 | France |
| D014570 |
| Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |