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This proposed clinical trial, REACH, will enroll 538 persons with hypertension. All subjects will continue with their prescribed medications. Our main objective is to assess whether preventive e-counseling (provided through a website of the Heart and Stroke Foundation) improves blood pressure and cardiovascular risk status over a 12-month interval. REACH will also evaluate improvement in lifestyle behaviors that include diet, exercise, smoking, and adherence to prescribed medications. Finally, we will quantify the amount of e-counseling support that is required during REACH to evoke a significant reduction in blood pressure. It is hypothesized that e-Counseling (vs. Control) will significantly improve blood pressure and lifestyle behaviours at the 12-month assessment. The findings of this trial will provide information that is critical to our understanding of how internet-based programs can help to improve blood pressure and to reduce the risk for cardiovascular disease.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| e-Counseling plus Usual Care | Experimental |
| |
| e-Info Control plus Usual Care | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| e-Counseling plus Usual Care | Behavioral | 28 emails will be sent proactively over a 12-month period. Emails will be sent weekly for the first 4 months, biweekly from months 5 to 8, and monthly from months 9 to 12. Each email will contain an e-link to lifestyle counseling activities designed to enhance motivation and skill to initiate and maintain lifestyle change. e-Counseling includes video-based education and counseling as well as e-tools to self-monitor and reinforce adherence to self-management behavior for exercise, diet, prescribed medications and smoke-free living. |
| Measure | Description | Time Frame |
|---|---|---|
| Blood Pressure | Systolic blood pressure, diastolic blood pressure, pulse pressure | 12-month |
| lipoprotein cholesterol | total, low-density, and total/high-density ratio | 12-month |
| 10-year absolute risk for Cardiovascular Heart Disease. | 12-month |
| Measure | Description | Time Frame |
|---|---|---|
| 4-day step count recorded by accelerometry | 12-month | |
| 24-hour urinary sodium excretion | 12-month | |
| salivary cotinine |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Robert P Nolan, Ph.D | Behavioural Cardiology Research Unit, University Health Network | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Vancouver Coastal Health | Vancouver | British Columbia | Canada | |||
| London Health Science Center |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31669047 | Derived | Liu S, Tanaka R, Barr S, Nolan RP. Effects of self-guided e-counseling on health behaviors and blood pressure: Results of a randomized trial. Patient Educ Couns. 2020 Mar;103(3):635-641. doi: 10.1016/j.pec.2019.10.007. Epub 2019 Oct 19. | |
| 30006474 | Derived | Nolan RP, Feldman R, Dawes M, Kaczorowski J, Lynn H, Barr SI, MacPhail C, Thomas S, Goodman J, Eysenbach G, Liu S, Tanaka R, Surikova J. Randomized Controlled Trial of E-Counseling for Hypertension: REACH. Circ Cardiovasc Qual Outcomes. 2018 Jul;11(7):e004420. doi: 10.1161/CIRCOUTCOMES.117.004420. |
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| ID | Term |
|---|---|
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D000068237 | Distance Counseling |
| ID | Term |
|---|---|
| D003376 | Counseling |
| D008605 | Mental Health Services |
| D004191 | Behavioral Disciplines and Activities |
| D003153 | Community Health Services |
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|
| Control | Behavioral | The control group will receive general educational material on heart healthy living. 28 emails will be sent proactively over a 12-month period. Emails will be sent weekly for the first 4 months, biweekly from months 5 to 8, and monthly from months 9 to 12. |
|
smoke-free living measured by salivary cotinine. Measured only in smokers |
| 12-month |
| Fruit and vegetable intake | Diet History Questionnaire | 12-month |
| London |
| Ontario |
| Canada |
| Grey Bruce Health Unit | Owen Sound | Ontario | Canada |
| University Health Network (Toronto Gen Hosp Site) | Toronto | Ontario | M5G 2N2 | Canada |
| 29752248 | Derived | Tanaka R, Nolan RP. Psychobehavioral Profiles to Assist Tailoring of Interventions for Patients With Hypertension: Latent Profile Analysis. J Med Internet Res. 2018 May 11;20(5):e149. doi: 10.2196/jmir.8757. |
| 23965936 | Derived | Nolan RP, Liu S, Feldman R, Dawes M, Barr S, Lynn H, Gwardy-Sridhar F, Thomas SG, Goodman J, Oh P, Kaczorowski J, Chessex C, Hachinski V, Shoemaker K. Reducing risk with e-based support for adherence to lifestyle change in hypertension (REACH): protocol for a multicentred randomised controlled trial. BMJ Open. 2013 Aug 21;3(8):e003547. doi: 10.1136/bmjopen-2013-003547. |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |
| D019114 | Remote Consultation |
| D012017 | Referral and Consultation |
| D011364 | Professional Practice |
| D009934 | Organization and Administration |
| D006298 | Health Services Administration |
| D017216 | Telemedicine |
| D003695 | Delivery of Health Care |
| D010346 | Patient Care Management |