Hepcidin Levels in Preterm Infants

Hepcidin Levels in Preterm Infants Receiving Blood Transfusion and During Sepsis.

A recently isolated peptide hormone, hepcidin, is thought to be the principal regulator of iron homeostasis. Hepcidin acts by limiting intestinal iron absorption and promoting iron retention in reticuloendothelial cells. The aims of this study were to determine serum hepcidin levels in preterm infants who receive blood transfusion and preterm infants having sepsis, in order to assess possible relationships between hepcidin and serum iron, serum ferritin,in iron load situations.

Inclusion Criteria:

• Preterm < 38 weeks gestation
• Need of blood test for anemia or suspected sepsis

Exclusion Criteria:

• Major congenital anomalies
• Birth Asphyxia