Oral Sodium Blood Pressure in Normal Weight, Overweight and Obese Volunteers

Simplification of the Test of Sensibility in the Salt: Preliminary Study at the Child and the Adult

The primary objective of this study is to analyze the sensitivity of blood pressure to oral salt intake. Matched male and female participants will be selected as normal weight, overweight, and obese.

Participating subjects will have a first visit with blood pressure measurement and a blood sample. In two consecutive phases of one week, subjects will receive 12 pills of sodium (6 grams) or corresponding placebo. Blood pressure will be measured at the end of each phase.

Inclusion Criteria:

• Informed consent
• Age 18-45 for adults and 6-8 for children

Exclusion Criteria:

• African ethnicity (known to affect blood pressure sensitivity to salt)
• Chronic condition affecting blood pressure
• Diabetes (known to affect blood pressure sensitivity to salt)
• Hypertension