Hepatitis B Vaccine in Patients With Inflammatory Bowel Disease

Assessment of Hepatitis B Vaccination Efficacy in Patients With Inflammatory Bowel Diseases

The objective is to assess the efficacy of Hepatitis B Virus vaccination in a population of IBD patients treated with immunosuppressive medications.

Inclusion Criteria:

• Male/female ≥ 18 years of age
• Evidence of IBD as diagnosed by clinical, laboratory imaging and endoscopic criteria.
• Treated with at least one immunosuppressive medication at the time of study initiation
• Provided written informed consent.

Exclusion Criteria:

• Pregnant women
• Diagnosis of chronic viral hepatitis B
• Any major acute medical event in the 30 days prior to recruitment that necessitated hospitalization ( acute myocardial infarction, CVA, pulmonary emboli, sepsis, major trauma)
• Any other chronic inflammatory condition not related to IBD ( connective tissue disease, Chronic liver disease, COPD, poorly controlled diabetes mellitus)
• Active hematologic or oncologic diseases