A Randomized Clinical Trial of the Effect of Pimecrolimus Cream 1% Compared With Topical Corticosteroid in Treatment of Erosive Oral Lichen Planus | NCT01524744 | Trialant
Unknown statusInterventionalPhase 2Updated Feb 2, 2012
A Randomized Clinical Trial of the Effect of Pimecrolimus Cream 1% Compared With Topical Corticosteroid in Treatment of Erosive Oral Lichen Planus
ClinicalTrials.gov ID
NCT01524744
Lead Sponsor
Mashhad University of Medical SciencesOTHER
Overall Status
Unknown status
Study Type
Interventional
Phase
Phase 2
Enrollment
40Estimated
Last Update Posted
Feb 2, 2012Estimated
Start Date
Mar 2009
Primary Completion Date
Oct 2012Estimated
Completion Date
Dec 2012Estimated
Brief Summary
The purpose of this study is to compare the effect of topical Pimecrolimus with adcortyl on erosive-atrophic 0ral lichen planus in a randomized clinical trial study.
Oral Lichen Planus
Pimecrolimus ointment
Adcortyl
Ages Eligible for Study
Child (0-17)Adult (18-64)Older Adult (65+)
Sexes Eligible for Study
All
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Biopsy confirmed oral lichen planus in combination with a compatible clinical appearance was used for diagnosis.
Exclusion Criteria:
Unable to undergo oral biopsy for diagnosis
Systemic diseases or malignancy
Pregnancy
Lesion/lesions with dysplasia/ history of allergic reaction to corticosteroids or immunomodulatory drugs.
Lesions adjacent to amalgam filling were also excluded from this study.