Effect of the Salbutamol on Mechanical Properties of Respiratory System

Effect of the Use of Salbutamol on the Mechanical Properties of the Respiratory System of Healthy Individuals, Smokers and COPD Patients

The aim of this study is to assess the bronchodilator response of salbutamol on respiratory mechanics of healthy individuals, smokers and COPD with varying degrees of airway obstruction.

Clinical evaluation will be conducted and anthropometric measurements, then the pulmonary function tests: forced oscillation technique (FOT), whole body plethysmography, spirometry and-administration of salbutamol aerosol for assessment of bronchodilator response. After 20 minutes, the individual will be evaluated again following the same sequence.

Inclusion Criteria:

• healthy individuals, smokers and patients with chronic obstructive pulmonary disease.

Exclusion Criteria:

• healthy subjects: no history of smoking respiratory infection and disease respiratory
• smokers and chronic obstructive pulmonary disease patients: asthma and other respiratory diseases.