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Impaired gastric emptying may cause dyspeptic symptoms including nausea, vomiting and even nutritionnal impairment. Delay in gastric emptying may result from antro-pyloro-duodenal motility impairement.
The aim of this study is therefore to measure antro-pyloro-duodenal motor activity in patients with idiopathic gastroparesis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control group | Healthy volunteers | ||
| Idiopathic gastroparesis | Idiopathic gastroparesis |
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| Measure | Description | Time Frame |
|---|---|---|
| antro-pyloro-duodenal pressure | the main outcome is the pressure measured using pressure sensors within the antrum, the pylorus, and the first part of the duodenum. This will be measured during 3h fast. Pressures measured in the antrum, the pylorus, and the duodenum wiil be compared between healthy volunteers and gastroparetic patients | 3h |
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Inclusion Criteria:
Exclusion Criteria:
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Idiopathic gastroparesis and healthy volunteers
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| Name | Affiliation | Role |
|---|---|---|
| Guillaume Gourcerol, MD, PhD | University Hospital, Rouen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de Physiologie | Rouen | Haute Normandie | 76000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37874655 | Derived | Soliman H, Wuestenberghs F, Desprez C, Leroi AM, Melchior C, Gourcerol G. Physiological characterization of gastric emptying using high-resolution antropyloroduodenal manometry. Am J Physiol Gastrointest Liver Physiol. 2024 Jan 1;326(1):G16-G24. doi: 10.1152/ajpgi.00101.2023. Epub 2023 Oct 24. |
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| ID | Term |
|---|---|
| D018589 | Gastroparesis |
| ID | Term |
|---|---|
| D013272 | Stomach Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D010243 | Paralysis |
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| D009461 |
| Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |